LN733 Alprazolam

Description

1. Comprehensive Scientific Overview
LN733 Alprazolam is a high-purity batch of the renowned triazolobenzodiazepine compound, Alprazolam. As a leading compound in its class, Alprazolam is primarily researched for its potent anxiolytic, sedative, hypnotic, and muscle relaxant properties, which stem from its positive allosteric modulation of the GABA-A receptor in the central nervous system. A common question in research is ‘Alprazolam vs Xanax’ – it is crucial to understand that Xanax is a well-known brand name for medications containing Alprazolam as the active pharmaceutical ingredient (API). Our LN733 product is the pure chemical entity itself, manufactured to the highest pharmaceutical standards, making it an essential reference material for analytical and developmental laboratories.

2. Advanced Chemical Specifications & Properties

• Chemical Name: 8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
• Synonyms: Alprazolam API, Alprazolam Base
• CAS Number: 28981-97-7
• Molecular Formula: C₁₇H₁₃ClN₄
• Molecular Weight: 308.76 g/mol
• Appearance: Fine, white to off-white crystalline powder
• Purity: ≥99% (USP/Ph. Eur. Grade, HPLC-verified)
• Solubility: Soluble in ethanol, DMSO, and acetone; very slightly soluble in water
• Storage: Store in a tight, light-resistant container at controlled room temperature (15–30°C)
• Stability: 36 months when stored under recommended conditions

3. Authorized Research Applications
Our premium LN733 Alprazolam is intended exclusively for controlled research and development purposes. Its primary applications include:

1. Pharmaceutical Development & Quality Control

• Reference Standard: Serves as a primary standard for quantifying Alprazolam dosage in finished pharmaceutical products (tablets, extended-release formulations) using HPLC, UPLC, and GC-MS methods
• API Sourcing: Used in the R&D of new generic formulations, requiring a pure and reliable source of the active ingredient
• Impurity Profiling: Essential for identifying and quantifying related substances and degradation products to ensure product safety and stability

2. Forensic & Clinical Toxicology

• Calibration & Verification: The gold-standard reference material for calibrating equipment in forensic labs to accurately identify and quantify alprazolam in biological samples
• Metabolic Studies: Research into the metabolic pathway of alprazolam (primarily to alpha-hydroxyalprazolam) for toxicological and pharmacokinetic analysis

3. Pre-Clinical Pharmacological Research

• Receptor Binding Studies: Investigation of its binding affinity and efficacy at different GABA-A receptor subunit compositions to understand its subtype selectivity
• Comparative Efficacy: Research to understand the effects of different Alprazolam doses in vitro and in animal models, answering questions like ‘what does alprazolam 0.5 mg do’ at a mechanistic level
• Safety Pharmacology: Studies on therapeutic index, drug interactions, and potential side effects

4. Understanding Alprazolam’s Profile
A key part of research involves understanding its clinical context:

• Alprazolam uses primarily involve the management of anxiety disorders and panic disorder, with or without agoraphobia
• Research into ‘alprazolam what is it used for’ also explores its off-label applications, such as chemotherapy-induced nausea or depression with anxious distress
• Alprazolam dosage is a critical variable, with research doses ranging from low (0.25 mg – 0.5 mg equivalents) to high, depending on the study objective

5. CRITICAL SAFETY & HANDLING PROTOCOL
WARNING: ALPRAZOLAM IS A POTENT SCHEDULED SUBSTANCE. It has a high potential for dependence, abuse, and severe withdrawal symptoms, including seizures. It is strictly NOT intended for human consumption. This product is sold solely as an analytical reference standard and chemical for use in legally authorized research settings.

Mandatory Safety Protocols for Researchers:

• Legal Compliance: Researchers must possess the appropriate DEA and/or national regulatory licenses for handling Schedule IV controlled substances
• Environment: Handle in a controlled, secure laboratory environment
• Personal Protective Equipment (PPE): Wear nitrile gloves, a lab coat, and safety goggles to prevent accidental exposure
• Administrative Controls: Maintain meticulous, auditable inventory logs in a dedicated controlled substance ledger. Store in a double-locked, secure safe with access limited to essential personnel only
• Waste Disposal: All waste must be collected and disposed of according to strict DEA and EPA regulations for controlled substance waste

6. Ordering & Packaging Information
Available for sale only to verified and accredited institutions with the proper controlled substance licenses:

• 100 mg (Analytical Reference Standard)
• 1 g (Research & Development Quantity)
• 5 g (Process Development – Limited Availability)
• Custom Quantities (For approved pharmaceutical manufacturers)

Every Order Includes:

• Certificate of Analysis (CoA): Detailed report conforming to USP/Ph. Eur. standards, including HPLC chromatogram, water content, residue on ignition, and related substances analysis
• Material Safety Data Sheet (MSDS): Comprehensive safety and handling instructions
• Regulatory Documentation: Packed with necessary paperwork for controlled substance tracking
• Secure Packaging: Sealed in a plastic vial within a controlled substance bottle, placed in a tamper-evident bag within anonymous outer packaging