Medetomidine, CAS 86347-15-1

Description

1. Premier Pharmaceutical Overview
Medetomidine Hydrochloride (CAS 86347-15-1) stands as a highly potent and selective alpha-2 adrenoceptor agonist, representing a cornerstone of modern veterinary sedation and analgesia. As a leading Medetomidine manufacturer and supplier, we provide this premium API to veterinary pharma companies worldwide. For those in the pharmaceutical industry researching ‘what is Medetomidine’, it is the powerful active ingredient behind renowned branded products like Dexdomitor (from Zoetis) and Zenalpha.

A critical pharmacological distinction lies in Medetomidine vs Dexmedetomidine; where Medetomidine is a racemic mixture, Dexmedetomidine is its pure, active dextro-isomer. Our product is the pure Medetomidine Hydrochloride API, manufactured to exacting standards for use in pharmaceutical development, research, and professional compounding for the global veterinary market.

We serve as a reliable Medetomidine distributor for clients across the United States (Medetomidine USA), Canada, Brazil, Mexico, and beyond, offering competitive Medetomidine cost for bulk quantities.

2. Elite Chemical & Functional Specifications

• Chemical Name: Medetomidine Hydrochloride
• Synonyms: Medetomidine HCl
• CAS Number: 86347-15-1
• Molecular Formula: C₁₃H₁₆N₂ · HCl
• Molecular Weight: 236.74 g/mol (free base: 200.28)
• Appearance: Fine, white to off-white crystalline powder
• Purity: ≥99% (HPLC-verified)
• Solubility: Freely soluble in water and methanol
• Storage: Store in a tight, light-resistant container at 2–8°C
• Drug Class: Potent alpha-2 adrenergic receptor agonist
• Key Function: Induces dose-dependent sedation, analgesia, and muscle relaxation. Its effects are rapidly reversible with specific antagonists.

3. Authorized Applications & Uses
Our premium Medetomidine Hydrochloride API is exclusively for the development and compounding of veterinary pharmaceutical products by verified businesses and Medetomidine manufacturers.

1. Veterinary Pharmaceutical Manufacturing

• Sedative & Analgesic Formulations: The primary API in injectable solutions used as a tranquilizer for dogs, cats, and other animals. It is the key component in products like Domitor for dogs (the original brand name) and its successor, Dexdomitor veterinary solution.
• Pre-Anesthetic Medication: Used to facilitate smooth inductions of general anesthesia, significantly reducing the required dose of induction and maintenance agents.
• Procedural Sedation: Ideal for formulating sedatives for minor surgical procedures, imaging (MRI, CT), and thorough clinical examinations.

2. Veterinary Compounding

• Custom Dosage Forms: Allows licensed compounding pharmacists to create tailored formulations for specific patient needs or species for which commercial products are not available.
• Dosage Adjustment: Essential for creating precise concentrations, especially critical for following specific guidelines like dexmedetomidine dose dog mg/kg protocols.

3. Research & Development

• New Product Development: Used by R&D teams to develop new generic formulations or novel delivery systems for veterinary sedation.
• Comparative Efficacy Studies: Research into the pharmacological profile, including studies on Medetomidine side effects and the efficacy of different Medetomidine reversal agents like atipamezole.

4. Pharmacological Profile & Safety
Understanding the drug’s profile is paramount for safe formulation:

• Mechanism: As an alpha-2 agonist, it inhibits the release of norepinephrine, leading to profound sedation and analgesia.
• Reversibility: A major safety feature is that its effects are completely reversible with alpha-2 antagonists, a process known as reversal.
• Side Effects: Common side effects can include bradycardia, transient hypertension followed by hypotension, and decreased respiratory rate. These are manageable and predictable in a clinical setting.
• Veterinary Use: Medetomidine for dogs and other animals is well-established, but it is a prescription-only substance that must be used under veterinary supervision.

5. Critical Regulatory & Safety Protocol
WARNING: MEDETOMIDINE IS A POTENT PRESCRIPTION VETERINARY PHARMACEUTICAL API. It is NOT for human use. It is NOT for direct animal administration. It must be expertly formulated into a sterile, finished dosage form by qualified professionals in a compliant facility. Handling requires appropriate PPE to prevent exposure.

Mandatory Safety Protocols for Handlers:

• Regulatory Compliance: All buyers must be verified pharmaceutical manufacturers, licensed compounding pharmacies, or accredited veterinary research institutions.
• Environment: Handle in a controlled environment with adequate ventilation.
• Personal Protective Equipment (PPE): Mandatory use of nitrile gloves, a lab coat, safety goggles, and a respirator to prevent inhalation or skin contact.
• Administrative Controls: Maintain strict inventory logs and store in a secure, controlled environment.

6. Order Now – For Verified Businesses Only
Formulate the Gold Standard in Veterinary Sedation.
Purchase Medetomidine from a trusted, reliable supplier. Our certified Medetomidine Hydrochloride ensures the efficacy and safety of your veterinary sedative products. We are a leading 86347-15-1 manufacturer and distributor, offering seamless ordering and global delivery.

BULK & CUSTOM QUANTITIES AVAILABLE: Scale your production with our flexible supply options. Order Medetomidine in quantities that meet your manufacturing needs.

Every Order Includes:

• Certificate of Analysis (CoA) with HPLC purity data
• Material Safety Data Sheet (MSDS)
• Regulatory Compliance Documentation
• Secure, Tamper-Evident Packaging